Recombinant Human TGF β1 (rh-TGF β1)
General description:
The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transformation of fibroblasts and recently it has been implicated in the formation of skin tumors.
CAS NO.:
Source: HEK293 (No animal components are used in the manufacturing process of this product, animal-free material.)
Form: Lyophilized
Mol. Weight: 12.8 kDa
Appearance: White Power
Purity: ≥98% (SDS-PAGE)
Specific Activity: 2.0×10^7IU/mg
Endotoxin: < 1.EU/μg (kinetic LAL)
Synonyms: Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor
Reconstitution: Dissolve with distilled water
Package: 50ug, 500ug, 1mg, 5mg,10mg
Storage&Shift life: -20ºC 2years
Application: Cell Culture and research
Limitations: For LABORATORY RESEARCH USE ONLY and is not approved for use in humans or clinical.
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Recombinant Protein AG(r-PAG) |
LRP010 |
Recombinant Peptostreptococcus magnus Protein L r-PPL |
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Recombinant Human Interferon γ(rh-IFN γ) |
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Recombinant Human Fibronectin (rh-FN) |
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Recombinant Human Lactotransferrin (LTF) |
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Recombinant Human alpha 1 Antitrypsin rh-AAT |
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Recombinant Human Superoxide Dismutase (Cu.Zn-SOD) |
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Recombinant Human Tissue Factor rh-TF |
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Recombinant Human Vascular
endothelial growth factor (rh-VEGF) |
LRP018 |
Recombinant Human Tumor Necrosis Factor α rh-TNFα |
LRP019 |
Recombinant Human Basic Fibroblast Growth Factor(rHubFGF) |
LRP020 |
Recombinant Human G-CSF (rh G-CSF) |
LRP021 |
Recombinant Human M-CSF (rh M-CSF) |
LRP022 |
Recombinant Human GM-CSF |
LRP023 |
Recombinant Human Platelet Derived Growth Factor-BB (PDGF-BB) |
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Recombinant Long Arg3 Human Insulin-like Growth Factor (rh-LR3-IGF1) |
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Recombinant Human Stem Cell Factor Recombinant Human SCF (rh-SCF) |
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Recombinant Human TGF β1 (rh-TGF β1) |
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